In general Donor Horse Serum possesses a higher quality than horse serum which can be collected once in slaughterhouse. Collection of raw material can be performed in more controlled and documented manner from donor animals and a closed herds. Using a fully aseptic collection method, contamination risk is much lower. Furthermore, in contrast to slaughtered horses, Donor Horse Serum; in general, has a lower endotoxin content and exhibits a lower level of batch-to-batch variation.